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Open the appserver.ini file, then add row {*}StartSysInDB=1* to the Environment section

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  \[P12DB\] SourcePath=C:\TOTVS 12\Microsiga\protheus\apo\ RootPath=C:\TOTVS 12\Microsiga\protheus_data CtreeRootPath=C:\TOTVS 12\Microsiga\protheus_data StartPath=\system\ x2_path= RpoDb=top RpoLanguage=Portuguese RpoVersion=120 LocalFiles=CTREE Trace=0 localdbextension=.dtc HELPSERVER=localhost:8079 TopMemoMega=1 DBAlias=P12DB DBServer=localhost DBDatabase=MSSQL DBPort=7890 StartSysInDB=1

Important:
After initialization of environment is concluded, the key STARTSYSINDB *must not* be removed from the configuration file of the environment. Removing the key may lead to problems in the Protheus environment. 

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